human genome organization slideshare

‘Acquiring complete knowledge of the organization, structure and function of human genome – the master blueprint of each of us – is the broad aim of Human Genome Project.’ With the target of three billion base pairs in human genome to be sequenced and by 1990- 100,000 had been analysed. In the wake of the U.S. Human Genome Project, the answer seemed to be a pretty resounding "no." The typical organization of the genome is. Accessory genes are interspersed within the structural genes at the 3’-end of the genome. The human genome, like the genomes of all other living animals, is a collection of long polymers of DNA. This Lecture talks about Genome Organization. The hereditary material i.e. Human genome project (HGP) was an international scientific research project which got successfully completed in the year 2003 by sequencing the entire human genome of 3.3 billion base pairs. Human genome consists of three billion base pairs Adenine, Cytosine, Guanine, Thymine ; Printing out the A,C,G,T would fill over 150,000 telephone book pages The genome organization, transcription, translation, and processing of human C3 and C5 are schematically illustrated in Fig. This Lecture talks about Genome Organization. The Human Genome-Stats. 1.Human C3 and C5 structural genes are located on chromosome 19p13.3-p13.2 and 9q33, respectively [30, 31].Although C3 (41 kb) and C5 (79 kb) genes are quite different in size, their intron-exon organization is very similar, with each consisting of 41 exons [7, 11]. Genome organization 1.ppt - Free download as Powerpoint Presentation (.ppt), PDF File (.pdf), Text File (.txt) or view presentation slides online. Learn more about the history and science behind the Human Genome Project. Genome organization in viruses, prokaryotes and eukaryotes. The HGP led to the growth of bioinformatics which is a vast field of research. Human Genome Project, an international collaboration that determined, stored, and rendered publicly available the sequences of almost all the genetic content of the chromosomes of the human organism, otherwise known as the human genome. 5’-leader-UTR-replicase-S(Spike)-E(Envelope)-M(Membrane)-N(Nucleocapsid)-3’-UTR-poly(A) tail. In 2004, for example, Francis Collins, then head of the National Human Genome Research Institute and now director of the National Institutes of Health, called race a “flawed” and “weak” concept and argued that science needed to move beyond race. Genomic organization refers to the linear order of DNA elements and their division into chromosomes. DNA (deoxyribonucleic acid) of an organism is composed of a sequence of four nucleotides in a specific pattern, which encode information as a function of their order. Accessory proteins are not needed for replication in tissue culture but appear to be important in viral pathogenesis. 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